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Article

Modulation of prostate cancer genetic risk by omega-3 and omega-6 fatty acids.

The Journal of clinical investigation - 1 Jul 2007

Berquin Isabelle M, Min Younong, Wu Ruping, Wu Jiansheng, Perry Donna, Cline J Mark, Thomas Mike J, Thornburg Todd, Kulik George, Smith Adrienne, Edwards Iris J, D'Agostino Ralph, Zhang Hao, Wu Hong, Kang Jing X, Chen Yong Q

Abstract excerpt

Although a causal role of genetic alterations in human cancer is well established, it is still unclear whether dietary fat can modulate cancer risk in a predisposed population. Epidemiological studies suggest that diets rich in omega-3 polyunsaturated fatty acids reduce cancer incidence. To determine the influence of fatty acids on prostate cancer risk in animals with a defined genetic lesion, we used...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 17607361
DOI: 10.1172/JCI31494
PMCID: PMC1890998

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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