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Article

Antagonistic control of lysosomal fusion by Rab14 and the Lyst-related protein LvsB.

Traffic (Copenhagen, Denmark) - 1 May 2013

Kypri Elena, Falkenstein Kristin, De Lozanne Arturo

Abstract excerpt

While loss of the protein Lyst causes abnormal lysosomes in patients with Chediak-Higashi syndrome, the contribution of Lyst to lysosome biology is not known. Previously we found that the Dictyostelium ortholog of Lyst, LvsB, is a cytosolic protein that associates with lysosomes and post-lysosomes to prevent their inappropriate fusion. Here we provide three lines of evidence that indicate that LvsB contributes to...

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Identifiers

PMID: 23387437
DOI: 10.1111/tra.12058
PMCID: PMC3622840

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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