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Article

HIF-1 alpha expression is associated with an atheromatous inflammatory plaque phenotype and upregulated in activated macrophages.

Atherosclerosis - 1 Dec 2007

Vink Aryan, Schoneveld Arjan H, Lamers Dennis, Houben Anna J S, van der Groep Petra, van Diest Paul J, Pasterkamp Gerard

Abstract excerpt

OBJECTIVE: Angiogenesis and inflammation are important features in atherosclerotic plaque destabilization. The transcription factor hypoxia-inducible factor-1 alpha (HIF-1 alpha) is a key regulator of angiogenesis and is also involved in inflammatory reactions. We studied HIF-1 alpha expression i...

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Source

Identifiers

PMID: 17606258
DOI: 10.1016/j.atherosclerosis.2007.05.026

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17606258-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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