Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Dynamic regulation of MTHFR mRNA expression and C677T genotype modulate mortality in coronary artery disease patients after revascularization.

Thrombosis research - 1 Jan 2007

Pereira Alexandre C, Miyakawa Ayumi A, Lopes Neuza H M, Soares Paulo R, de Oliveira Sergio A, Cesar Luiz A M, Ramires Jose F, Hueb Whady, Krieger Jose Eduardo

Abstract excerpt

INTRODUCTION: A large body of evidence links plasma homocysteine (Hcy) concentrations and cardiovascular disease. A common MTHFR polymorphism (C677T) leads to a variant with reduced activity and associated with increased Hcy levels. Coronary surgery precipitates a significant and sustained increase in the blood concentrations of Hcy and elevated levels of plasma Hcy have been associated to saphenous vein (SV)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Coronary Artery Bypass
Share to Coronary Artery Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Data Collection

Share to Gene Expression Regulation, Enzymologic

Share to Methylenetetrahydrofolate Reductase (NADPH2)

Share to Mortality

Share to Postoperative Complications

Share to Saphenous Vein

Source

Identifiers

PMID: 17604826
DOI: 10.1016/j.thromres.2007.03.004

Genes

MTHFR
CAD

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Dynamic regulation of MTHFR mRNA expression and C677T genotype modulate mortality in coronary artery disease patients after revascularization.PMID 17604826Read ↗

Hyperhomocysteinemia and mortality after coronary artery bypass grafting.Semantic proximity Read ↗

Influence of 677 C-->T polymorphism of methylenetetrahydrofolate reductase on medium-term prognosis after acute coronary syndromes.Semantic proximity Read ↗

Correlation between C677T MTHFR gene polymorphism, plasma homocysteine levels and the incidence of CAD.Semantic proximity Read ↗

Thermolabile methylenetetrahydrofolate reductase in coronary artery disease.Semantic proximity Read ↗

Cardiac allograft vascular disease after orthotopic heart transplantation: methylenetetrahydrofolate reductase gene polymorphism C677T does not account for rapidly progressive forms.Semantic proximity Read ↗

Methylenetetrahydrofolate reductase gene polymorphism and its association with coronary artery disease.Semantic proximity Read ↗

[MTHFR genetic variability on coronary artery disease development].Semantic proximity Read ↗

Association of polymorphism in the thermolabile 5, 10-methylene tetrahydrofolate reductase gene and hyperhomocysteinemia with coronary artery disease.Semantic proximity Read ↗

Relationship between plasma homocysteine levels and saphenous vein graft disease after coronary artery bypass grafts.Semantic proximity Read ↗

MTHFR polymorphism and risk of periprocedural myocardial infarction after coronary stenting.Semantic proximity Read ↗

Methylenetetrahydrofolate reductase 677 C/T genotype and cardiovascular disease mortality in postmenopausal women.Semantic proximity Read ↗

The T(-786)C endothelial nitric oxide synthase genotype predicts cardiovascular mortality in high-risk patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.