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Article

SNP (-617C>A) in ARE-like loci of the NRF2 gene: a new biomarker for prognosis of lung adenocarcinoma in Japanese non-smoking women.

PloS one - 1 Jan 2013

Okano Yasuko, Nezu Uru, Enokida Yasuaki, Lee Ming Ta Michael, Kinoshita Hiroko, Lezhava Alexander, Hayashizaki Yoshihide, Morita Satoshi, Taguri Masataka, Ichikawa Yasushi, Kaneko Takeshi, Natsumeda Yutaka, Yokose Tomoyuki, Nakayama Haruhiko, Miyagi Yohei, Ishikawa Toshihisa

Abstract excerpt

PURPOSE: The transcription factor NRF2 plays a pivotal role in protecting normal cells from external toxic challenges and oxidative stress, whereas it can also endow cancer cells resistance to anticancer drugs. At present little information is available about the genetic polymorphisms of the NRF2 gene and their clinical relevance. We aimed to investigate the single nucleotide polymorphisms in the NRF2 gene as a...

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Identifiers

PMID: 24040073
DOI: 10.1371/journal.pone.0073794
PMCID: PMC3770684

Genes

MDM2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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