Article
Polymorphisms of Nrf2, an antioxidative gene, are associated with blood pressure in Japanese.
Nagoya journal of medical science - 1 Feb 2014
Shimoyama Yasuhiko, Mitsuda Yoko, Hamajima Nobuyuki, Niwa Toshimitsu
Abstract excerpt
Nuclear factor-erythroid 2 (NF-E2)-related factor 2 (Nrf2) is a transcription factor that regulates the expression of antioxidant genes by activating Nrf2-antioxidant response element (ARE) pathway. This study aimed to investigate association of Nrf2 gene single nucleotide polymorphisms (SNPs), rs35652124 (A --> G) and rs6721961 (C --> A), with various laboratory data in 464 health evaluation examinees. The...
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