Article
Fractioned DNA pooling: a new cost-effective strategy for fine mapping of quantitative trait loci.
Genetics - 1 Aug 2007
Korol A, Frenkel Z, Cohen L, Lipkin E, Soller M
Abstract excerpt
Selective DNA pooling (SDP) is a cost-effective means for an initial scan for linkage between marker and quantitative trait loci (QTL) in suitable populations. The method is based on scoring marker allele frequencies in DNA pools from the tails of the population trait distribution. Various analytical approaches have been proposed for QTL detection using data on multiple families with SDP analysis. This article...
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