Article
Multiple-marker mapping for selective DNA pooling within large families.
Journal of dairy science - 1 Jul 2008
Dolezal M, Schwarzenbacher H, Soller M, Sölkner J, Visscher P M
Abstract excerpt
Selective DNA pooling is a very powerful method for quantitative trait loci (QTL) mapping. It considerably reduces genotyping costs while maintaining high statistical power. Applied to a daughter design, milk samples of offspring with extreme phenotypic values for a trait of interest are assigned to high and low groups, respectively, and within each group the pooled DNA is used for densitometric estimation of...
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