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Article

Selective DNA pooling for determination of linkage between a molecular marker and a quantitative trait locus.

Genetics - 1 Dec 1994

Darvasi A, Soller M

Abstract excerpt

Selective genotyping is a method to reduce costs in marker-quantitative trait locus (QTL) linkage determination by genotyping only those individuals with extreme, and hence most informative, quantitative trait values. The DNA pooling strategy (termed: "selective DNA pooling") takes this one step further by pooling DNA from the selected individuals at each of the two phenotypic extremes, and basing the test for...

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Identifiers

PMID: 7896115
DOI: 10.1093/genetics/138.4.1365
PMCID: PMC1206272

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