Article
Implications of strain- and species-level sequence divergence for community and isolate shotgun proteomic analysis.
Journal of proteome research - 1 Aug 2007
Denef Vincent J, Shah Manesh B, Verberkmoes Nathan C, Hettich Robert L, Banfield Jillian F
Abstract excerpt
The recent surge in microbial genomic sequencing, combined with the development of high-throughput liquid chromatography-mass-spectrometry-based (LC/LC-MS/MS) proteomics, has raised the question of the extent to which genomic information of one strain or environmental sample can be used to profile proteomes of related strains or samples. Even with decreasing sequencing costs, it remains impractical to obtain...
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