Article
Proteogenomic analysis of polymorphisms and gene annotation divergences in prokaryotes using a clustered mass spectrometry-friendly database.
Molecular & cellular proteomics : MCP - 1 Jan 2011
de Souza Gustavo A, Arntzen Magnus Ø, Fortuin Suereta, Schürch Anita C, Målen Hiwa, McEvoy Christopher R E, van Soolingen Dick, Thiede Bernd, Warren Robin M, Wiker Harald G
Abstract excerpt
Precise annotation of genes or open reading frames is still a difficult task that results in divergence even for data generated from the same genomic sequence. This has an impact in further proteomic studies, and also compromises the characterization of clinical isolates with many specific genetic variations that may not be represented in the selected database. We recently developed software called multistrain...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
