Article
Effect of the mutation rate and background size on the quality of pathogen identification.
Bioinformatics (Oxford, England) - 15 Oct 2007
Reed Chris, Fofanov Viacheslav, Putonti Catherine, Chumakov Sergei, Slezak Tom, Fofanov Yuriy
Abstract excerpt
MOTIVATION: Genomic-based methods have significant potential for fast and accurate identification of organisms or even genes of interest in complex environmental samples (air, water, soil, food, etc.), especially when isolation of the target organism cannot be performed by a variety of reasons. Despite this potential, the presence of the unknown, variable and usually large quantities of background DNA can cause...
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