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Article

Proteogenomics: concepts, applications and computational strategies.

Nature methods - 1 Nov 2014

Nesvizhskii Alexey I

Abstract excerpt

Proteogenomics is an area of research at the interface of proteomics and genomics. In this approach, customized protein sequence databases generated using genomic and transcriptomic information are used to help identify novel peptides (not present in reference protein sequence databases) from mass spectrometry-based proteomic data; in turn, the proteomic data can be used to provide protein-level evidence of gene...

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Topics

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Share to Databases, Nucleic Acid
Share to Databases, Protein
Share to High-Throughput Nucleotide Sequencing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mass Spectrometry

Share to Protein Isoforms

Share to Proteome

Share to Proteomics

Share to Sequence Analysis, Protein

Source

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Identifiers

PMID: 25357241
DOI: 10.1038/nmeth.3144
PMCID: PMC4392723

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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