STAT3 polymorphism predicts interferon-alfa response in patients with metastatic renal cell carcinoma.

doi:10.1200/JCO.2006.09.8897

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Article

STAT3 polymorphism predicts interferon-alfa response in patients with metastatic renal cell carcinoma.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 1 Jul 2007

Ito Noriyuki, Eto Masatoshi, Nakamura Eijiro, Takahashi Atsushi, Tsukamoto Taiji, Toma Hiroshi, Nakazawa Hayakazu, Hirao Yoshihiko, Uemura Hirotsugu, Kagawa Susumu, Kanayama Hiroomi, Nose Yoshiaki, Kinukawa Naoko, Nakamura Tsuyoshi, Jinnai Nobuyoshi, Seki Toyokazu, Takamatsu Masanobu, Masui Yoshihiro, Naito Seiji, Ogawa Osamu

Abstract excerpt

PURPOSE: To clarify the effect of genetic polymorphisms on the response to interferon alfa (IFN-alpha) for metastatic renal cell carcinoma (MRCC), and to find a reliable molecular marker to select those patients with MRCC who would benefit from IFN-alpha immunotherapy. PATIENTS AND METHODS: We carried out an association study in which 463 single nucleotide polymorphisms (SNPs) in 33 candidate genes were genotyped...

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PMID: 17602083
DOI: 10.1200/JCO.2006.09.8897

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STAT3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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