Article
A Single-Nucleotide Polymorphism (rs1131243) of the Transforming Growth Factor Beta Signaling Pathway Contributes to Risk of Acute Rejection in Chinese Renal Transplant Recipients.
Medical science monitor : international medical journal of experimental and clinical research - 1 Dec 2019
Zheng Ming, Yang Haiwei, Li Wencheng, Zhou Jiajun, Wei Jintao, Wang Zijie, Guo Miao, Chen Hao, Sun Li, Han Zhijian, Tao Jun, Ju Xiaobing, Tan Ruoyun, Wei Jifu, Gu Min
Abstract excerpt
BACKGROUND Acute rejection (AR) is a common complication of kidney transplantation. The transforming growth factor beta (TGF-ß) signaling pathway has been observed to be involved in several cellular functions. Our study aimed to investigate the correlations between single-nucleotide polymorphisms (SNPs) in TGF-ß-related genes and the risk of AR in renal transplant recipients. MATERIAL AND METHODS This...
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