Article
Polymorphisms in the IL-13 and IL-4R genes are associated with the development of renal cell carcinoma.
Annals of oncology : official journal of the European Society for Medical Oncology - 1 Aug 2012
Chu H, Wang M, Yan F, Zhong D, Shi D, Ma L, Pan X, Qin C, Yin C, Zhang Z
Abstract excerpt
BACKGROUND: Cytokines are the important modulators that bind to their relevant receptors in response to some stimuli to mediate the homeostasis. It has been suggested that the imbalance of immune system of the host might affect the generation of diseases, including cancers. PATIENTS AND METHODS: We investigated the association between six functional polymorphisms of IL-4, IL-13, and IL-4R genes and susceptibility...
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