N-acetylation and hydroxylation polymorphisms in type II diabetics with microvascular disturbances.

doi:10.1007/s002280050226

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Article

N-acetylation and hydroxylation polymorphisms in type II diabetics with microvascular disturbances.

European journal of clinical pharmacology - 1 Jan 1997

Gawrońska-Szklarz B, Górnik W, Pawlik A, Kunicki P, Wójcicki J, Sitkiewicz D, Sych Z

Abstract excerpt

The N-acetylation and hydroxylation (CYP2D6) genetic polymorphisms were assessed in 43 healthy subjects and in 84 type II (non-insulin-dependent) diabetics. The proportions of slow and fast acetylators as well as poor and extensive metabolisers in a group of diabetics suffering from microvascular...

Topics

Acetylation
Adult
Aged
Debrisoquin
Diabetes Mellitus, Type 2
Diabetic Angiopathies
Female
Gene Frequency
Humans
Hydroxylation
Male
Middle Aged
Phenotype
Polymorphism, Genetic
Sulfamethazine

Source

Open in PubMed

Identifiers

PMID: 9112055
DOI: 10.1007/s002280050226

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9112055-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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