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Associations between α+‐Thalassemia andPlasmodium falciparumMalarial Infection in Northeastern Tanzania

29 Jun 2007

Abstract excerpt

BACKGROUND: The 2 most common hemoglobinopathies, sickle cell trait and alpha (+)-thalassemia, confer partial resistance to fatal forms of malaria, but the molecular basis for this protection is still not understood. Examination of the relationship between these traits and malaria transmission intensity may provide insights into the protection afforded. METHODS: The distribution of the 2 traits was assessed among...

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PMID: 17597460
DOI: 10.1086/519390

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