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Article

Malaria Host Candidate Genes Validated by Association With Current, Recent, and Historical Measures of Transmission Intensity.

The Journal of infectious diseases - 1 Jul 2017

Sepúlveda Nuno, Manjurano Alphaxard, Campino Susana G, Lemnge Martha, Lusingu John, Olomi Raimos, Rockett Kirk A, Hubbart Christina, Jeffreys Anna, Rowlands Kate, Clark Taane G, Riley Eleanor M, Drakeley Chris J

Abstract excerpt

Background: Human malaria susceptibility is determined by multiple genetic factors. It is unclear, however, which genetic variants remain important over time. Methods: Genetic associations of 175 high-quality polymorphisms within several malaria candidate genes were examined in a sample of 8096 individuals from northeast Tanzania using altitude, seroconversion rates, and parasite rates as proxies of historical,...

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Identifiers

PMID: 28541483
DOI: 10.1093/infdis/jix250
PMCID: PMC5853769

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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