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An investigation of the protective effect of alpha+-thalassaemia against severe Plasmodium falciparum amongst children in Kumasi, Ghana

2012-01-01

Abstract excerpt

Background: The alpha+-thalassaemias are the most common monogenic disorders of humans, characterised by microcytic and hypochromic anaemia. Their high frequency reflects selective advantage against death from Plasmodium falciparum malaria. The most common type of alpha+- thalassaemia amongst people of African descent is the -α3.7 deletional type and affects 26-33% of Ghanaians. Plasmodium falciparum malaria is a...

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Literature Corpus work
b4230039-e94d-5b7e-9e48-b918c466b249
DOI
10.34737/8z421
Open publication

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An investigation of the protective effect of alpha+-thalassaemia against severe Plasmodium falciparum amongst children in Kumasi, GhanaDOI 10.34737/8z421
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