Article
An investigation of the protective effect of alpha+-thalassaemia against severe Plasmodium falciparum amongst children in Kumasi, Ghana.
International journal of laboratory hematology - 1 Feb 2014
Opoku-Okrah C, Gordge M, Kweku Nakua E, Abgenyega T, Parry M, Robertson C, Smith C L
Abstract excerpt
INTRODUCTION: Several factors influence the severity of Plasmodium falciparum; here, we investigate the impact of alpha+-thalassaemia genotype on P. falciparum parasitemia and prevalence of severe anaemia amongst microcytic children from Kumasi, Ghana. METHODS: Seven hundred and thirty-two children (≤10 years) with P. falciparum were categorised into normocytic and microcytic (mean cell volume ≤76 fL). Microcytic...
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