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Article

Frontotemporal lobar degeneration with ubiquitin-positive inclusions: a molecular genetic update.

Neuro-degenerative diseases - 1 Jan 2007

van der Zee Julie, Gijselinck Ilse, Pirici Daniel, Kumar-Singh Samir, Cruts Marc, Van Broeckhoven Christine

Abstract excerpt

Frontotemporal lobar degeneration (FTLD) is a clinically, pathologically and genetically highly complex disorder. In the last few years enormous progress has been made in dissecting the genetic etiology of FTLD. Mutations have been identified in the progranulin gene (PGRN), the charged multivesicular body protein 2B gene (CHMP2B) and the valosin-containing protein gene (VCP). Mutations in these genes all lead to...

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Identifiers

PMID: 17596717
DOI: 10.1159/000101847

Genes

VCP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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