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Article

The neuropathology and clinical phenotype of FTD with progranulin mutations.

Acta neuropathologica - 1 Jul 2007

Mackenzie Ian R A

Abstract excerpt

Mutations in the progranulin gene (PGRN), on chromosome 17q21, have recently been identified as a major cause of familial frontotemporal dementia (FTD). These cases have a characteristic pattern of neuropathology that is a distinct subtype of frontotemporal lobar degeneration with ubiquitinated i...

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Identifiers

PMID: 17458552
DOI: 10.1007/s00401-007-0223-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17458552-2026-09-02.1. Manifest publication-graph-cohort-2026-09-02.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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