Article
The molecular genetics and neuropathology of frontotemporal lobar degeneration: recent developments.
Neurogenetics - 1 Nov 2007
Mackenzie Ian R A, Rademakers Rosa
Abstract excerpt
The past year has seen a number of significant advances in our understanding of the neuropathological and molecular genetic basis of frontotemporal lobar degeneration (FTLD). Whereas, in the past, most attention focused on FTLD associated with tau-based pathology and microtubule associated protein tau gene (MAPT) mutations, there has recently been greater attention paid to non-tau FTLD. FTLD with tau-negative,...
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