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Article

Construction of genetically defined double aro mutants of Salmonella typhi.

Vaccine - 1 Nov 1991

Hone D M, Harris A M, Chatfield S, Dougan G, Levine M M

Abstract excerpt

The construction of genetically defined, double aro mutant strains CVD906 and CVD908, which were derived from Salmonella typhi strain ISP1820 (a recent isolate of S. typhi from Chile) and from laboratory strain Ty2, respectively, is described. Strains CVD906 and CVD908 differ from previously described aro mutants of S. typhi as their aro deletion mutations do not extend beyond the limits of the mutated aro genes,...

Topics

Adolescent
Animals
Bacterial Vaccines
Chromosome Deletion
DNA Replication
DNA, Bacterial
Female
Genes, Bacterial
Genetic Complementation Test
Humans
Mice
Phenotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Salmonella typhi

Typhoid Fever

Virulence

Source

Identifiers

PMID: 1759503
DOI: 10.1016/0264-410x(91)90218-u

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1759503-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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