Construction of an aroA mutant of Salmonella serotype Gallinarum: its effectiveness in immunization against experimental fowl typhoid.

doi:10.1016/0264-410x(93)90288-9

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Article

Construction of an aroA mutant of Salmonella serotype Gallinarum: its effectiveness in immunization against experimental fowl typhoid.

Vaccine - 1 Jan 1993

Griffin H G, Barrow P A

Abstract excerpt

An aroA mutant was produced from a virulent strain of Salmonella Gallinarum, the causative agent of fowl typhoid in poultry, by Tn10 insertional inactivation and deletion. The mutant was highly attenuated for chickens. A single intramuscular immunization of 2-week-old chickens with 10(7) mutant o...

Topics

Animals
Bacterial Vaccines
Chickens
Genes, Bacterial
Immunization
Mutation
Salmonella
Salmonella Infections, Animal
Serotyping
Vaccines, Attenuated

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