Article
Polymorphisms in the tumor necrosis factor-alpha gene in Turkish women with pre-eclampsia and eclampsia.
Acta medica Okayama - 1 Jun 2007
Pazarbaşi Ayfer, Kasap Mülkiye, Güzel Ali Irfan, Kasap Halil, Onbaşioğlu Meliz, Ozbakir Burcu, Demirkazik Ayşe, Ozgünen Fatma Tuncay, Gürtunç Evrim
Abstract excerpt
The genetic background predisposing pregnant women to pre-eclampsia/eclampsia (PE/E) is still unknown. The aim of the current study was to investigate whether there is an association between the TNF-alpha-308 and 850 polymorphisms and PE or eclampsia. In this study, 40 cases of eclampsia, 113 cases of PE and 80 normotensive control cases were genotyped for the TNF-alpha-G-308A and C-850 polymorphisms. At position...
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