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Article

Tumour necrosis factor (-308A) polymorphism in pre-eclampsia: meta-analysis of 16 case-control studies.

The Australian & New Zealand journal of obstetrics & gynaecology - 1 Dec 2008

Bombell Sarah, McGuire William

Abstract excerpt

BACKGROUND: The guanine to adenine transition at position -308 nucleotides in the tumour necrosis factor promoter region (TNF -308A) is a putative genetic risk factor for pre-eclampsia/eclampsia (PE/E). However, association studies have reported conflicting findings and have generally been underpowered to exclude modest effect sizes. AIM: To assess and synthesise the available evidence for the association of the...

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Source

Identifiers

PMID: 19133041
DOI: 10.1111/j.1479-828X.2008.00924.x

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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