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Article

Tumour necrosis factor-alpha gene haplotype is associated with pre-eclampsia.

Molecular human reproduction - 1 Jun 2005

Saarela Tanja, Hiltunen Mikko, Helisalmi Seppo, Heinonen Seppo, Laakso Markku

Abstract excerpt

We determined whether polymorphisms in the promoter region of the tumour necrosis factor alpha (TNF-alpha) gene contributes to differences in susceptibility to develop pre-eclampsia. The study involved 133 pre-eclamptic and 115 healthy pregnant women who were genotyped for the G-308A polymorphism of the TNF-alpha gene. The frequency of the G-308A allele was more common in the pre-eclampsia group than among the...

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PMID: 15901845
DOI: 10.1093/molehr/gah182

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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