Maternal tumor necrosis factor receptor 2 gene variants associated with pre-eclampsia in Tunisian women.

doi:10.1111/jog.12066

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Article

Maternal tumor necrosis factor receptor 2 gene variants associated with pre-eclampsia in Tunisian women.

The journal of obstetrics and gynaecology research - 1 Aug 2013

Said Lamia, Faleh Raja, Smida Samia, Laajili Hayet, Sakouhi Mohamed, Bel Hadj Jrad Besma

Abstract excerpt

AIM: The tumor necrosis factor receptor 2 (TNFR2) is expressed in placental tissue and it is involved in immune responses, inflammation, angiogenesis and blood pressure regulation; which makes it an attractive pre-eclampsia (PE) candidate gene. Furthermore, TNFR2 expression is altered in the first trimester in placentas of women who are destined to develop PE. Therefore, we examined the association between...

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PMID: 23799986
DOI: 10.1111/jog.12066

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