Article
Analysis of C-850T and G-308A polymorphisms of the tumor necrosis factor-alpha gene in Maya-Mestizo women with preeclampsia.
Hypertension in pregnancy - 1 Jan 2007
Canto-Cetina Thelma, Canizales-Quinteros Samuel, de la Chesnaye Elsa, Coral-Vázquez Ramón, Méndez Juan Pablo, Canto Patricia
Abstract excerpt
OBJECTIVE: To determine whether polymorphisms in the TNF-alpha promoter gene are associated with preeclampsia. METHODS: 105 women with preeclampsia and 200 controls were genotyped for the G-308A and C-850T polymorphisms by RFLP. Differences in allele, genotype, and haplotype frequencies between groups were assessed. RESULTS: The genotypic and allelic distribution of both polymorphisms was similar between groups....
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