Article
Association between heat shock protein 70/Hom genetic polymorphisms and uveitis in patients with sarcoidosis.
Investigative ophthalmology & visual science - 1 Jul 2007
Spagnolo Paolo, Sato Hiroe, Marshall Sara E, Antoniou Katerina M, Ahmad Tariq, Wells Athol U, Ahad Muhammad A, Lightman Susan, du Bois Roland M, Welsh Kenneth I
Abstract excerpt
PURPOSE: The predisposition to sarcoidosis, a systemic granulomatous disorder of unknown etiology, is genetically determined, and genetics appears also to drive the disease down distinct phenotypic pathways. This study was undertaken to test the hypothesis that sarcoidosis-related uveitis represents a genetically distinct disease subset, by investigating single nucleotide polymorphisms (SNPs) in the HSP-70/1 and...
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