Article
Sarcoidosis: genes and microbes--soil or seed?
Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG - 1 Jun 2001
McGrath D S, Goh N, Foley P J, du Bois R M
Abstract excerpt
Sarcoidosis is a multi-organ granulomatous disorder that is characterised by the accumulation of CD4+ T-lymphocytes resulting in a Th-1 type immune response. Although our understanding of the immune response in sarcoidosis has improved in recent years through studies of bronchoalveolar lavage cells and fluid, the genetic predisposition and trigger factors (and their interrelationship) remain unclear. Previous...
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