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Article

Variation in the lymphotoxin-alpha/tumor necrosis factor locus modifies risk of erythema nodosum in sarcoidosis.

The Journal of investigative dermatology - 1 Aug 2009

McDougal Kathryn E, Fallin M Daniele, Moller David R, Song Zhimin, Cutler David J, Steiner Lori L, Cutting Garry R

Abstract excerpt

Sarcoidosis is a multi-system inflammatory disease with organ involvement that varies by race and sex. Family studies indicate that genes play a role in the etiology and extent of organ involvement in sarcoidosis. In this study, we evaluated whether 25 variants distributed in 19 genes with a known role in inflammation were associated with erythema nodosum status in 659 sarcoidosis patients and 658 controls from A...

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Identifiers

PMID: 19225544
DOI: 10.1038/jid.2008.456
PMCID: PMC2877485

Genes

TNF
LTA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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