Acetaldehyde, polymorphisms and the cardiovascular system.

doi:10.1002/9780470511848.ch4

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Article

Acetaldehyde, polymorphisms and the cardiovascular system.

Novartis Foundation symposium - 1 Jan 2007

Yin Shih-Jiun, Peng Giia-Sheun

Abstract excerpt

To date, the only genes that have been consistently replicated across racial and ethnic groups to influence alcoholism vulnerability are polymorphisms in the alcohol-metabolizing enzymes, i.e. cytosolic alcohol dehydrogenase 1B (ADH1B) and mitochondrial aldehyde dehydrogenase 2 (ALDH2). Both the variant ADHIB*2 and ALDH2*2 alleles significantly protect against developing alcoholism. The protection has been...

Topics

Acetaldehyde
Alcohol Dehydrogenase
Alcoholism
Aldehyde Dehydrogenase
Aldehyde Dehydrogenase, Mitochondrial
Analysis of Variance
Blood Flow Velocity
Blood Pressure
Chromatography, Gas
Chromatography, High Pressure Liquid
Echocardiography, Doppler

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Ethanol

Ethnicity

Gene Frequency

Genetic Predisposition to Disease

Genotype

Humans

Logistic Models

Source

Open in PubMed

Identifiers

PMID: 17590986
DOI: 10.1002/9780470511848.ch4

Genes

ALDH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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