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Article

Acetaldehyde, polymorphisms and the cardiovascular system.

Novartis Foundation symposium - 1 Jan 2007

Yin Shih-Jiun, Peng Giia-Sheun

Abstract excerpt

To date, the only genes that have been consistently replicated across racial and ethnic groups to influence alcoholism vulnerability are polymorphisms in the alcohol-metabolizing enzymes, i.e. cytosolic alcohol dehydrogenase 1B (ADH1B) and mitochondrial aldehyde dehydrogenase 2 (ALDH2). Both the variant ADHIB*2 and ALDH2*2 alleles significantly protect against developing alcoholism. The protection has been...

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Source

Identifiers

PMID: 17590986
DOI: 10.1002/9780470511848.ch4

Genes

ALDH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Acetaldehyde, polymorphisms and the cardiovascular system.PMID 17590986Read ↗

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Pharmacokinetic and pharmacodynamic basis for overcoming acetaldehyde-induced adverse reaction in Asian alcoholics, heterozygous for the variant ALDH2*2 gene allele.Semantic proximity Read ↗

Genetic Associations of Alcohol and Aldehyde Dehydrogenase With Alcohol Dependence and Their Mechanisms of ActionSemantic proximity Read ↗

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