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Article

Differential roles of the Leloir pathway enzymes and metabolites in defining galactose sensitivity in yeast.

Molecular genetics and metabolism - 1 Jan 2000

Ross Kerry L, Davis Charity N, Fridovich-Keil Judith L

Abstract excerpt

The metabolism of galactose via enzymes of the Leloir pathway: galactokinase, galactose-1-P uridylyltransferase, and UDP galactose-4'-epimerase, is a process that has been conserved from Escherichia coli through humans. Impairment of this pathway in patients results in the disease galactosemia. Despite decades of study, the underlying pathophysiology in galactosemia remains unknown. Here we have defined the...

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Identifiers

PMID: 15464425
DOI: 10.1016/j.ymgme.2004.07.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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