Article
G protein signaling governing cell fate decisions involves opposing Galpha subunits in Cryptococcus neoformans.
Molecular biology of the cell - 1 Sept 2007
Hsueh Yen-Ping, Xue Chaoyang, Heitman Joseph
Abstract excerpt
Communication between cells and their environments is often mediated by G protein-coupled receptors and cognate G proteins. In fungi, one such signaling cascade is the mating pathway triggered by pheromone/pheromone receptor recognition. Unlike Saccharomyces cerevisiae, which expresses two Galpha subunits, most filamentous ascomycetes and basidiomycetes have three Galpha subunits. Previous studies have defined...
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