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Article

G-protein signaling mediates asexual development at 25 degrees C but has no effect on yeast-like growth at 37 degrees C in the dimorphic fungus Penicillium mameffei.

Eukaryotic cell - 1 Jun 2002

Zuber Sophie, Hynes Michael J, Andrianopoulos Alex

Abstract excerpt

The ascomycete Penicillium marneffei is an opportunistic human pathogen exhibiting a temperature-dependent dimorphic switch. At 25 degrees C, P. marneffei grows as filamentous multinucleate hyphae and undergoes asexual development, producing uninucleate spores. At 37 degrees C, it forms uninucleate yeast cells which divide by fission. We have cloned a gene encoding a G alpha subunit of a heterotrimeric G protein...

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Identifiers

PMID: 12455992
DOI: 10.1128/EC.1.3.440-447.2002
PMCID: PMC118015

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Source receipt: pubmed, retrieved 7 Sept 2026.

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G-protein signaling mediates asexual development at 25 degrees C but has no effect on yeast-like growth at 37 degrees C in the dimorphic fungus Penicillium mameffei.PMID 12455992Read ↗

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