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Article

Strong associations of psoriasis with antigen processing LMP and transport genes TAP differ by gender and phenotype.

Genes and immunity - 1 Sept 2007

Krämer U, Illig T, Grune T, Krutmann J, Esser C

Abstract excerpt

Psoriasis, a skin disease with autoimmune features, can be triggered and exacerbated by genetic and environmental factors. Chemicals can break tolerance to self-antigens by interfering with antigen processing and presentation; therefore, proteins involved in antigen processing may affect susceptibility. We test here whether variants of immunoproteasome subunits LMP2 and LMP7, or antigen peptide transport proteins...

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Source

Identifiers

PMID: 17581627
DOI: 10.1038/sj.gene.6364404

Genes

TAP1
TAP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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