Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A fetal cyclooxygenase-2 gene polymorphism is associated with placental malperfusion.

International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists - 1 Jul 2007

Polydorides Alexandros D, Kalish Robin B, Witkin Steven S, Baergen Rebecca N

Abstract excerpt

Prostaglandin levels vary during pregnancy, mostly under the control of the inducible enzyme cyclooxygenase-2 (COX-2). The expression of COX-2 has been associated with ischemic events in the heart and brain, but its direct effect on human placental perfusion has not been previously examined. The purpose of this study was to investigate whether a functional polymorphism in the COX-2 gene that controls enzyme...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cyclooxygenase 2
Share to Fetal Growth Retardation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Histocytochemistry

Share to Infant, Newborn

Share to Placenta

Share to Placenta Diseases

Share to Pregnancy

Share to Pregnancy Complications

Source

Identifiers

PMID: 17581413
DOI: 10.1097/01.pgp.0000236950.56785.a8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A fetal cyclooxygenase-2 gene polymorphism is associated with placental malperfusion.PMID 17581413Read ↗

The epidemiology of placental features: Associations with gestational age and neonatal outcomeSemantic proximity Read ↗

Term preeclampsia is associated with minimal histopathological placental features regardless of clinical severitySemantic proximity Read ↗

Cognitive outcome and cyclo-oxygenase-2 gene (-765 G/C) variation in the preterm infant.Semantic proximity Read ↗

Phenotypes of maternal vascular malperfusion placental pathology and adverse pregnancy outcomes: A retrospective cohort study.Semantic proximity Read ↗

Genetic polymorphisms in the fibrinolytic system of placentas with massive perivillous fibrin deposition.Semantic proximity Read ↗

[Recent knowledge on mechanisms underlying development of pre-eclampsia].Semantic proximity Read ↗

-765 G→C and -1195 A→G promoter variants of the cyclooxygenase-2 gene decrease the risk for preeclampsia.Semantic proximity Read ↗

A genetic association study of maternal and fetal candidate genes that predispose to preterm prelabor rupture of membranes (PROM).Semantic proximity Read ↗

Aetiology of pre-eclampsia and thrombophilic genetic mutations.Semantic proximity Read ↗

COX-1 and COX-2 polymorphisms in susceptibility to cerebral palsy in very preterm infants.Semantic proximity Read ↗

The COX-2 G/C -765 polymorphism may modulate the occurrence of cerebrovascular ischemia.Semantic proximity Read ↗

Association between matrix metalloproteinase (MMP)-2 polymorphisms and MMP-2 levels in hypertensive disorders of pregnancy.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.