[Recent knowledge on mechanisms underlying development of pre-eclampsia].

Abstract excerpt

BACKGROUND: The present paper gives an overview of recent research on mechanisms underlying pre-eclampsia. Special attention is paid to immune reactions at the feto-maternal site and genetics linked to maternal susceptibility. RESULTS: The pathogenesis of pre-eclampsia may be seen as a two-stage process. Deficient trophoblast invasion and artery remodelling may underlie subsequent placental hypoperfusion....

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