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Efflux-Related Resistance to Norfloxacin, Dyes, and Biocides in Bloodstream Isolates of<i>Staphylococcus aureus</i>

19 Jun 2007

Abstract excerpt

Efflux is an important resistance mechanism in Staphylococcus aureus, but its frequency in patients with bacteremia is unknown. Nonreplicate bloodstream isolates were collected over an 8-month period, and MICs of four common efflux pump substrates, with and without the broad-spectrum efflux pump inhibitor reserpine, were determined (n = 232). A reserpine-associated fourfold decrease in MIC was considered...

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PMID: 17576828
DOI: 10.1128/aac.00430-07

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