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Article

Systematic Analysis of Efflux Pump-Mediated Antiseptic Resistance in Staphylococcus aureus Suggests a Need for Greater Antiseptic Stewardship.

mSphere - 15 Jan 2020

LaBreck Patrick T, Bochi-Layec Audrey C, Stanbro Joshua, Dabbah-Krancher Gina, Simons Mark P, Merrell D Scott

Abstract excerpt

Staphylococcus aureus-associated infections can be difficult to treat due to multidrug resistance. Thus, infection prevention is critical. Cationic antiseptics, such as chlorhexidine (CHX) and benzalkonium chloride (BKC), are liberally used in health care and community settings to prevent infection. However, increased administration of antiseptics has selected for S. aureus strains that show reduced...

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Identifiers

PMID: 31941819
DOI: 10.1128/mSphere.00959-19
PMCID: PMC6968660

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