Article
Clonal relatedness is a predictor of spontaneous multidrug efflux pump gene overexpression in Staphylococcus aureus.
International journal of antimicrobial agents - 1 May 2015
Schindler Bryan D, Jacinto Pauline L, Buensalido Joseph Adrian L, Seo Susan M, Kaatz Glenn W
Abstract excerpt
Increased expression of genes encoding multidrug resistance efflux pumps (MDR-EPs) contributes to antimicrobial agent and biocide resistance in Staphylococcus aureus. Previously identified associations between norA overexpression and spa type t002 meticillin-resistant S. aureus (MRSA), and a similar yet weaker association between mepA overexpression and type t008 meticillin-susceptible S. aureus (MSSA), in...
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