Article
Exploring the contribution of efflux on the resistance to fluoroquinolones in clinical isolates of Staphylococcus aureus.
BMC microbiology - 27 Oct 2011
Costa Sofia Santos, Falcão Celeste, Viveiros Miguel, Machado Diana, Martins Marta, Melo-Cristino José, Amaral Leonard, Couto Isabel
Abstract excerpt
BACKGROUND: Antimicrobial resistance mediated by efflux systems is still poorly characterized in Staphylococcus aureus, despite the description of several efflux pumps (EPs) for this bacterium. In this work we used several methodologies to characterize the efflux activity of 52 S. aureus isolates resistant to ciprofloxacin collected in a hospital in Lisbon, Portugal, in order to understand the role played by...
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