Article
IL-33: A Sheep in Wolf’s Clothing?
12 Jun 2007
Abstract excerpt
Cytokines are soluble factors that regulate intercellular communication by binding to specific cell-surface receptors and activating cellular responses. A small subset of cytokines, however, has been recognized to act in an intracrine manner without being secreted. These molecules enter the nucleus and regulate gene transcription by binding nuclear coactivators or repressors. Interleukin-33 (IL-33), a cytokine...
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