Article
Association study between clinical response to rizatriptan and some candidate genes.
The journal of headache and pain - 1 Jun 2007
Asuni Carlo, Cherchi Allesandra, Congiu Donatella, Piccardi Maria P, Del Zompo Maria, Stochino Maria E
Abstract excerpt
The aim of this study was to test genetic differences in the clinical response to rizatriptan in patients affected by migraine without aura. These genetic differences could be explained by various genes, the HTR1B, encoding the 5-HT(1) receptor subtype, MAOA gene that encodes the monoamino-oxidase, the main metabolic enzyme of this triptan, SLC6A4 (gene encoding the serotonin transporter) and DRD(2) (gene...
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