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Article

Clinical susceptibility to migraine with aura is modified by dopamine D2 receptor (DRD2) NcoI alleles.

Neurology - 1 Jul 1997

Peroutka S J, Wilhoit T, Jones K

Abstract excerpt

Migraine has a major genetic component. Although most recent scientific studies have focused on the role of 5-hydroxytryptamine and neuropeptides in migraine, dopaminergic systems are also implicated in the pathogenesis. Therefore, the dopamine D2 receptor (DRD2) was analyzed as a candidate gene...

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Source

Identifiers

PMID: 9222191
DOI: 10.1212/wnl.49.1.201

Genes

DRD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-9222191-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Clinical susceptibility to migraine with aura is modified by dopamine D2 receptor (DRD2) NcoI alleles.PMID 9222191Read ↗

Comorbid migraine with aura, anxiety, and depression is associated with dopamine D2 receptor (DRD2) NcoI alleles.Semantic proximity Read ↗

The D2 receptor <i>Nco</i> I allele: Absence of allelic association with migraine with auraSemantic proximity Read ↗

New genetic evidence for involvement of the dopamine system in migraine with aura.Semantic proximity Read ↗

Association between dopamine receptor genes and migraine without aura in a Sardinian sample.Semantic proximity Read ↗

Dopamine receptor genes and migraine with and without aura: an association study.Semantic proximity Read ↗

Association of the T102C polymorphism of 5-HT2A receptor gene with aura in migraine.Semantic proximity Read ↗

Role of dopaminergic gene polymorphisms (DBH 19 bp indel and DRD2 Nco I) in genetic susceptibility to migraine in North Indian population.Semantic proximity Read ↗

Identification of a novel ANKK1 and other dopaminergic (DRD2 and DBH) gene variants in migraine susceptibility.Semantic proximity Read ↗

Angiotensin-converting enzyme gene deletion polymorphism determines an increase in frequency of migraine attacks in patients suffering from migraine without aura.Semantic proximity Read ↗

An investigation of the 5-HT2C receptor gene as a migraine candidate gene.Semantic proximity Read ↗

Two-stage case-control association study of dopamine-related genes and migraine.Semantic proximity Read ↗

An adenosine A2A receptor gene haplotype is associated with migraine with aura.Semantic proximity Read ↗

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