Article
Early gene-environment interactions: can they inform primary preventive strategies for asthma?
Seminars in respiratory and critical care medicine - 1 Jun 2007
von Mutius Erika, Le Souëf Peter Neils
Abstract excerpt
The concept of using gene-environment studies to discover mechanisms of asthma in early life is deceptively simple and attractive. To do so would appear to require a straightforward examination of relationships between a polymorphism and asthma-related phenotypes in young children. However, in reality, the process is far from simple and lack of appreciation of the complexity of this area of research has been one...
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