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Article

Time-dependent gene-environment interactions are essential drivers of asthma initiation and persistence.

Pediatric pulmonology - 1 May 2024

Chatziparasidis Grigorios, Chatziparasidi Maria R, Kantar Ahmad, Bush Andrew

Abstract excerpt

Asthma is a clinical syndrome caused by heterogeneous underlying mechanisms with some of them having a strong genetic component. It is known that up to 82% of atopic asthma has a genetic background with the rest being influenced by environmental factors that cause epigenetic modification(s) of gene expression. The interaction between the gene(s) and the environment has long been regarded as the most likely...

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Identifiers

PMID: 38380964
DOI: 10.1002/ppul.26935

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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